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New features to predict miRNA target sites in mRNAs

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In order to study gene regulation, it is necessary to identify the target sites of miRNA in mRNA. miRNAs have been the main point of research as its binding to mRNA degrades the target mRNA and also prevents the translation of target mRNAs [1-4]. The identification of miRNA target sites, target mRNAs and the potential functional roles of miRNA may be assigned. Continue reading “New features to predict miRNA target sites in mRNAs” »

Common features used to develop miRNA target prediction tools

in Algorithms by

As we have discussed the miRNAs, their formation, and functions (miRNA targets and their functions ) and an overview on some of the available  miRNA target prediction tools (miRNAs and their Target Prediction Tools: An Overview in previous articles. In this article, I have tried to give basic information about the common features which are involved in the formation of most of the miRNA target prediction algorithms and tools. Continue reading “Common features used to develop miRNA target prediction tools” »

Prediction of Protein-Protein Binding Affinity through their Amino Acid Sequence

in Algorithms/Tools by

Protein-protein interactions (PPIs) have become necessary in order to study many biological processes. In order to study the PPIs, the binding affinity among the proteins is predicted. Experimental prediction of PPIs requires expensive setup and is very tedious. Therefore, computational methods are used to predict the binding affinity, which is less time taking and provides accurate results. Continue reading “Prediction of Protein-Protein Binding Affinity through their Amino Acid Sequence” »

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