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Structural Identification of Macromolecules in solution with DARA web server

in Algorithms/Bioinformatics News/Softwares by

To study macromolecules in homogenous solution, a technique known as SAXS ( Small Angle X-ray Scattering) is used where the obtained scattering patterns are used to design the structure of macromolecules that are proteins, mucleic acids and protein:nucleic acid complexes. Continue reading “Structural Identification of Macromolecules in solution with DARA web server” »

Explained: CRISPR-ERA and CRISPR/Cas9 system

in Algorithms/Tools by

CRISPR/Cas9 system is a bacterial defence mechanism against bacteriophage infection. When a viral dna(Bacteriophage, in this case) integrates into the bacterial genome, it produces RNA which is taken up by Cas9. Continue reading “Explained: CRISPR-ERA and CRISPR/Cas9 system” »

MUSCLE: Tool for Multiple Sequence Alignment

in Algorithms/Softwares/Tools by

In my last article I discussed about the Multiple Sequence Alignment and its creation. Now in this article, I am going to explain the workflow of one of the MSA tool, i.e., MUSCLE. MUSCLE is a software which is used to create MSA of the sequences of interest.  Continue reading “MUSCLE: Tool for Multiple Sequence Alignment” »

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