The chains are removed from the protein structure just to avoid the complexity. But, we should make sure that the catalytic residues or the binding site do not fall between the two chains, in this case, we have to consider both the chains for docking.
Muniba is a Bioinformatician based in the South China University of Technology. She has cutting edge knowledge of bioinformatics tools, algorithms, and drug designing. When she is not reading she is found enjoying with the family. Know more about Muniba