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Why do we choose only one chain of protein for docking?

Browse QuestionsCategory: QuestionsWhy do we choose only one chain of protein for docking?
user asked 7 years ago

Please answer Why do we choose only one chain of protein for docking?

1 Answers
Dr. Muniba FaizaDr. Muniba Faiza Staff answered 7 years ago

The chains are removed from the protein structure just to avoid the complexity. But, we should make sure that the catalytic residues or the binding site do not fall between the two chains, in this case, we have to consider both the chains for docking.

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