Bioinformatics ReviewBioinformatics Review
Notification Show More
Font ResizerAa
  •  Home
  • Docking
  • MD Simulation
  • Tools
  • More Topics
    • Softwares
    • Sequence Analysis
    • Algorithms
    • Bioinformatics Programming
    • Bioinformatics Research Updates
    • Drug Discovery
    • Phylogenetics
    • Structural Bioinformatics
    • Editorials
    • Tips & Tricks
    • Bioinformatics News
    • Featured
    • Genomics
    • Bioinformatics Infographics
  • Community
    • BiR-Research Group
    • Community Q&A
    • Ask a question
    • Join Telegram Channel
    • Join Facebook Group
    • Join Reddit Group
    • Subscription Options
    • Become a Patron
    • Write for us
  • About Us
    • About BiR
    • BiR Scope
    • The Team
    • Guidelines for Research Collaboration
    • Feedback
    • Contact Us
    • Recent @ BiR
  • Subscription
  • Account
    • Visit Dashboard
    • Login
Font ResizerAa
Bioinformatics ReviewBioinformatics Review
Search
Have an existing account? Sign In
Follow US
Drug DiscoverySoftwareTools

Most widely used tools for drug-drug interaction prediction

Dr. Muniba Faiza
Last updated: May 27, 2024 8:43 am
Dr. Muniba Faiza
Share
2 Min Read
Most widely used tools for drug-drug interaction prediction Most widely used tools for drug-drug interaction prediction
SHARE

Drug-drug interaction is an important method in bioinformatics, especially in the case of treatment of serious diseases such as cancer. It tells us about the drug effect modified by another drug. In this article, we summarize a few useful tools for drug-drug interaction prediction.

Contents
1. NDD2. DPDDIReferences

There are quite a few predictors available for drug-drug interactions. We have discussed below the most widely used software including their availability.

1. NDD

NDD is a standalone tool for drug-drug interaction prediction based on neural networks [1]. It first calculates the drug similarities and Gaussian Interaction Profile similarities for each drug pair. After that, it selects a subset of similarities based on more information and less redundancy. Later, it creates a single matrix by integrating all selected matrices. Finally, for each drug pair, the two corresponding rows of the integrated matrix are fed to a two-layer neural network for classification [1].

The software is freely accessible at Github.

2. DPDDI

DPDDI is another software for drug-drug interaction prediction [2]. It predicts drug-drug interactions by extracting the network structure features of drugs from the network with a graph-convolutional network and a deep neural network as a predictor [2]. It does not consider the drug properties such as drugs’ biological and chemical properties. Since the software is a Tensorflow implementation of the DPDDI model, therefore, it requires TensorFlow (1.0 or later), python 2.7, networkx, scikit-learn, and scipy to be installed.

The software is freely available to download at Github.


References

  1. Rohani, N., Eslahchi, C. (2019). Drug-Drug Interaction Predicting by Neural Network Using Integrated Similarity. Sci Rep 9, 13645.
  2. Feng, YH., Zhang, SW. & Shi, JY. (2020). DPDDI: a deep predictor for drug-drug interactions. BMC Bioinformatics 21, 419.
TAGGED:drug-drug interactiondrug-drug interaction prediction
Share This Article
Facebook Copy Link Print
ByDr. Muniba Faiza
Follow:
Dr. Muniba is a Bioinformatician based in New Delhi, India. She has completed her PhD in Bioinformatics from South China University of Technology, Guangzhou, China. She has cutting edge knowledge of bioinformatics tools, algorithms, and drug designing. When she is not reading she is found enjoying with the family. Know more about Muniba
Leave a Comment

Leave a Reply Cancel reply

You must be logged in to post a comment.

- Advertisement -
Ad image
10 years of Bioinformatics Review: From a Blog to a Bioinformatics Knowledge Hub!
Editorial
Starting in Bioinformatics? Do This First!
Starting in Bioinformatics? Do This First!
Tips & Tricks
[Editorial] Is it ethical to change the order of authors’ names in a manuscript?
Editorial Opinion
Installing bbtools on Ubuntu
[Tutorial] Installing BBTools on Ubuntu (Linux).
Sequence Analysis Software Tools

You Might Also Like

Installing Snakemake on Ubuntu (Linux)
SoftwareTools

Installing Snakemake on Ubuntu (Linux)

December 1, 2021
SoftwareTools

Installing Roary and Prokka on Ubuntu

July 29, 2020
PhylogeneticsSoftwareTools

How to calculate dN, dS, and dN/dS ratio on a set of genes using MEGA?

May 20, 2020
installing exabayes on Ubuntu
PhylogeneticsSoftwareTools

[Tutorial] Installing Exabayes on Ubuntu (Linux).

May 26, 2025
Copyright 2024 IQL Technologies
  • Journal
  • Customer Support
  • Contact Us
  • FAQs
  • Terms of Use
  • Privacy Policy
  • Cookie Policy
  • Sitemap
Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?

Not a member? Sign Up