CRISPR/Cas9 system is a recently developed multi-purpose technology for genome editing [1,2] and its tool CRISPR-ERA/Cas9 is widely used as explained in the previous article . The possible applications of this system have been discussed by its developers  and have been successfully applied for genome editing, gene function identification, and for gene therapy in animals and human cells [5-9]. Recently, a group of Chinese researchers has reported the editing of a genome using CRISPR/Cas9 system in human embryo for the first time in history . The team has attempted to remove ‘harmful’ genetic codes to be potentially replaced by the ‘good’ ones. The results are published in Protein & Cell journal  but have opened a topic for debate over crossing the ethics of gene editing. Continue reading “Genome editing of human embryos using CRISPR/Cas9- crossing the ethics of gene editing?” »
AutoDock Vina is a bioinformatics tool which is used to perform in- silico docking of proteins with a ligand. It provides many options depending on the needs of a user. This tool offers blind docking and binding in a specific pocket as well, which is sometimes more demanding when the binding site is already known. This article will guide you to dock a protein with a ligand in a specific binding site/ pocket. Continue reading “How to perform docking in a specific binding site using AutoDock Vina?” »
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