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VISPR- A new tool to visualize CRISPR screening experiments

Tariq Abdullah

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VISPR- A new tool to visualize CRISPR screening experiments

As CRISPR/Cas9 is a well-known genome editing technology, it is important to explore and analyze CRISPR screening experiments. In this article, we discuss a new tool developed for better visualization of CRISPR screening experiments.

A new web-based tool called VISPR is developed to visualize CRISPR screening experiments [1]. VISPR stands for VISualization of crisPR screens. VISPR allows easy online analysis, visualization, and sharing of CRISPR screening data. VISPR also supports two other tools: BAGEL and JACKS. Additionally, VISPR allows users to visualize read count changes along with an interactive environment for gene exploration and viewing guide RNA locations [1].

How does VISPR work?

VISPR mainly consists of three modules: the front-end file parsing module, uniform file formats, and back-end visualization module. The front-end module processes files of screening analysis tools including MAGeCK, MAGeCK-VISPR, BAGEL, and JACKS. The uniform file formats scale the front-end and the back-end. The third visualization module processes the uniform file formats [1].

VISPR is available for Linux, macOS, and Windows environments. It is freely accessible at http://vispr-online.weililab.org/ and the source is available on GitHub.

For more details, read here.


References

  1. Cui, Y., Wang, Z., Köster, J. et al. VISPR-online: a web-based interactive tool to visualize CRISPR screening experiments. BMC Bioinformatics 22, 344 (2021).

Tariq is founder of Bioinformatics Review and CEO at IQL Technologies. His areas of expertise include algorithm design, phylogenetics, MicroArray, Plant Systematics, and genome data analysis. If you have questions, reach out to him via his homepage.

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