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An introduction to the predictors of pathogenic point mutations

in Algorithms/Softwares/Tools by

Single nucleotide variation is a change in a single nucleotide in a sequence irrespective of the frequency of the variation. Single nucleotide variants (SNVs) play a very important role in causing several diseases such as the tumor, cancer, etc. Many efforts have been made to identify the SNVs which were initially based on identifying non-synonymous mutations in coding regions of the genomes. Continue reading “An introduction to the predictors of pathogenic point mutations” »

How to install AutoDock Vina on Ubuntu?

in Softwares/Tools by

AutoDock Vina is one of the most popular software in Bioinformatics, known for the molecular docking simulations. I have already explained the docking procedure in my previous article. In this small tutorial, we will learn how to install AutoDock Vina on Ubuntu. Its installation on Ubuntu may be a tedious process, especially for the beginners due to the unfamiliarity of the Linux commands. It is expected to work on any version of Ubuntu, but make sure whether your system supports the 32- bit or 64- bit version. If you face any problem, then feel free to ask. Continue reading “How to install AutoDock Vina on Ubuntu?” »

Role of Information Theory, Chaos Theory, and Linear Algebra and Statistics in the development of alignment-free sequence analysis

in Algorithms/Sequence Analysis/Softwares by

Sequence alignment is a customary to not only find similar regions among a pair of sequences but also to study the structural, functional and evolutionary relationship between organisms. Many tools have been discovered to achieve the goal of alignment of a pair of sequences, separately for nucleotide sequence and amino acid sequence, BLOSSUM & PAM [1] are a few to name. Continue reading “Role of Information Theory, Chaos Theory, and Linear Algebra and Statistics in the development of alignment-free sequence analysis” »

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