Structural Bioinformatics

A collection of articles related to three-dimensional structure prediction of macromolecules such as protein, DNA, and RNA.

Latest Structural Bioinformatics News

How to predict binding pocket/site using CASTp server?

The CASTp server allows you to predict the binding sites in a…

Dr. Muniba Faiza Dr. Muniba Faiza

Video Tutorial: Calculating binding pocket volume using PyVol plugin.

This is a video tutorial for calculating binding pocket volume using the…

Dr. Muniba Faiza Dr. Muniba Faiza

Protein structure & folding information exploited from remote homologs.

Remote homologs are similar protein structures that share similar functions, but there…

Dr. Muniba Faiza Dr. Muniba Faiza

How to generate electron density map using Pymol?

Electron density maps are available for most of the protein structures in…

Dr. Muniba Faiza Dr. Muniba Faiza

How to install Kpax on Ubuntu (Linux)?

Kpax is a bioinformatics program to search and align protein structures .…

Tariq Abdullah Tariq Abdullah

How to run do_dssp command (mkdssp) in Gromacs 2022?

In the latest version of GROMACS (2022) , there are some issues…

Dr. Muniba Faiza Dr. Muniba Faiza

Extracting first and last residue from helix file in DSSP format.

Previously, we have provided a tutorial on using dssp_parser to extract all…

Dr. Muniba Faiza Dr. Muniba Faiza

SWISS-MODEL: Uses & Applications

SWISS-MODEL is a bioinformatics tool that is widely used for protein structure…

Dr. Muniba Faiza Dr. Muniba Faiza

I-TASSER: Uses & Applications

I-TASSER is another most widely used bioinformatics software. It is used for…

Dr. Muniba Faiza Dr. Muniba Faiza

Homology Modeling vs ab initio Protein Structure Prediction

In one of our previous articles, we explained the basic methodology involved…

Tariq Abdullah Tariq Abdullah

Tutorial: Basic protein structure modeling using MODELLER

SALI MODELLER is one of the most widely used command-line bioinformatics software…

Dr. Muniba Faiza Dr. Muniba Faiza

Methodology for Homology Modeling of a Simple Protein

Previously, we have explained the initial methods involved in the structure prediction…

Dr. Muniba Faiza Dr. Muniba Faiza

How to install DeepView-Swiss PDB Viewer on Linux?

DeepView (Swiss-PDB Viewer) is used to analyze multiple proteins simultaneously. Protein structure…

Tariq Abdullah Tariq Abdullah

Homology Modeling of α-Glucosidase Enzyme: 3D Structure Prediction

The word "Homology modeling", means comparative modeling or sometimes it is known…

Dr.Maria Dr.Maria

Biotite: A bioinformatics framework for sequence and structure data analysis

Sequence and structural data in bioinformatics are ever-increasing and the need for…

Dr. Muniba Faiza Dr. Muniba Faiza

ab-initio prediction of protein structure: An introduction

We have heard a lot about the ab-initio term in Bioinformatics, which…

Dr. Muniba Faiza Dr. Muniba Faiza

How to perform protein structure modeling using I-Tasser stand-alone tool?

I-Tasser stands for the iterative threading assembly refinement is a well-known tool…

Tariq Abdullah Tariq Abdullah

Structural analysis of FOXL2 gene and its role in kidney failure

FOXL2 gene codes for a protein belonging to the fork-head- winged helix…

Lakshmi Pattabhiraman Lakshmi Pattabhiraman