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Structural Bioinformatics

Homology Modeling of α-Glucosidase Enzyme: 3D Structure Prediction

in Structural Bioinformatics/Structure Prediction by

The word “Homology modeling”, means comparative modeling or sometimes it is known as Template-Based Modeling (TBM), which refers to develop a three dimensional model of a protein structure by extracting the keen information’s from already experimentally known structure of a homologous protein (the template).  The 3D Protein structural information provides great assistance to study the function of different proteins, ligands interactions, dynamics, and Protein-Protein Interactions (PPI). Continue reading “Homology Modeling of α-Glucosidase Enzyme: 3D Structure Prediction” »

Biotite: A bioinformatics framework for sequence and structure data analysis

in Sequence Analysis/Softwares/Structural Bioinformatics by

Sequence and structural data in bioinformatics are ever-increasing and the need for its analysis is ever-demanding likewise. As bioinformaticians analyze the data with their keen knowledge and reach important conclusions, similarly, bioinformaticists provide with the enhanced and advanced tools and software for data analysis. Continue reading “Biotite: A bioinformatics framework for sequence and structure data analysis” »

ab-initio prediction of protein structure: An introduction

in Algorithms/Structural Bioinformatics/Structure Prediction by

We have heard a lot about the ab-initio term in Bioinformatics, which could be difficult to understand for newbies in the field of bioinformatics. Today, we will discuss in detail what ab-initio is and what are the applicable methods for it. Continue reading “ab-initio prediction of protein structure: An introduction” »

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