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Sequence search against a set of local sequences (local database) using phmmer

in Proteomics/Sequence Analysis/Softwares by

PHMMER is a sequence analysis tool used for protein sequences (http://hmmer.org; version 3.1 b2). It is available online as a web server and as well as a part of the HMMER stand-alone package (http://hmmer.org; version 3.1 b2). HMMER offers various useful features such as multiple sequence alignment including the file format conversion.  Continue reading “Sequence search against a set of local sequences (local database) using phmmer” »

Disulphide Connectivity in Protein Tertiary Structure Prediction

in Bioinformatics News/Proteomics by

As the approach towards the protein structure prediction has increased and has been successful in most of the cases but still also a big challenge. To handle this situation, the Protein Structure prediction is divided in to separate sub classes to get the information about the whole system (i.e.,protein structure). One of these sub classes is Disulphide Connectivity. Under this, the disulphide bonds formed between non-adjacent Cysteine residues are identified that would be cross-linked from other possible residues. Continue reading “Disulphide Connectivity in Protein Tertiary Structure Prediction” »

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