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Muniba Faiza

Muniba Faiza has 49 articles published.

Benchmark databases for multiple sequence alignment: An overview

in Algorithms/Sequence Analysis/Softwares by

Multiple sequence alignment (MSA) is a very crucial step in most of the molecular analyses and evolutionary studies. Many MSA programs have been developed so far based on different approaches which attempt to provide optimal alignment with high accuracy. Basic algorithms employed to develop MSA programs include progressive algorithm [1], iterative-based [2], and consistency-based algorithm [3]. Some of the programs incorporate several other methods into the process of creating an optimal alignment such as M-COFFEE [4] and PCMA [5]. Continue reading “Benchmark databases for multiple sequence alignment: An overview” »

ab-initio prediction of protein structure: An introduction

in Algorithms/Structural Bioinformatics/Structure Prediction by

We have heard a lot about the ab-initio term in Bioinformatics, which could be difficult to understand for newbies in the field of bioinformatics. Today, we will discuss in detail what ab-initio is and what are the applicable methods for it. Continue reading “ab-initio prediction of protein structure: An introduction” »

An introduction to the predictors of pathogenic point mutations

in Algorithms/Softwares/Tools by

Single nucleotide variation is a change in a single nucleotide in a sequence irrespective of the frequency of the variation.¬†Single nucleotide variants (SNVs) play a very important role in causing several diseases such as the tumor, cancer, etc. Many efforts have been made to identify the SNVs which were initially based on identifying non-synonymous mutations in coding regions of the genomes. Continue reading “An introduction to the predictors of pathogenic point mutations” »

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