This is a video tutorial of Autodock Vina installation on Ubuntu, based on our existing tutorial.
Blind docking is done when the catalytic/binding residues are unknown in a protein, hence, the binding pocket is unknown. In a previous article, we showed how to perform site-specific docking using Autodock Vina, where we bound a ligand in a catalytic pocket of a protein. Now, this article will cover the blind docking using Autodock Vina. Continue reading “How to perform blind docking using AutoDock Vina?” »
If you want to get a quick idea about the non-synonymous vs synonymous (dN/dS) substitutions, you can easily use MEGA software . Although HYPHY/Datamonkey provides the best results regarding selection pressure analyses. MEGA also uses HYPHY program  to calculate the dN/dS substitutions rate. Here is how you can do it. Continue reading “How to calculate dN, dS, and dN/dS ratio on a set of genes using MEGA?” »