On the 31st of March 2020, Bioinformatics Review created a team of bioinformatics researchers from all over the world to find potential drug candidates for nCov-19. This group is a collaborative effort and works remotely from all over the world. This group has 150+ researchers from 21 Countries.
Updates
Read about our latest in silico vaccine candidate design against covid19.
Update: A multi-epitope in silico vaccine candidate designed for Covid-19
Read about our latest selection pressure study on spike glycoproteins of SARS-CoV.
Update: Selection analysis on spike glycoproteins of SARS-CoV
Read about our latest selection pressure study on spike glycoproteins of SARS-CoV-2.
Update: Selection analysis on spike glycoprotein of SARS-CoV-2
Read about our latest work on phylogenetics analysis of spike glycoproteins of SARS-CoV-2 and SARS-CoV.
Data
Find all the necessary files here.
Fig. 1 Phylogenetic tree of SARS-CoV-2 spike sequences with SARS-CoV spike sequences as an outgroup.
Fig. 2 MSA of all spike glycoprotein sequences of SARS-CoV-2 and SARS-CoV.
File 1 MSA of all spike glycoprotein sequences of SARS-CoV-2 and SARS-CoV showing conserved residues.
Fig. 3 Structure of Spike Glycoprotein (PDB ID: 6VXX) of SARS-CoV-2. The detected residues under positive selection are shown in red color.