Answer for Why are the hetatoms removed from the protein PDB file before docking?
The structure we are using is a crystal structure complexed with ligand(s),…
Answer for How do I know which result is better in docking?
Since you have downloaded the protein structure from PDB without any mutagenesis,…
Answer for should the docked ligand exactly fall on the ligand which we have?
Most of the time, when we dock in a specific site, the ligand…
Answer for Do all residues showing attachment to ligand contribute to the binding energy?
Sometimes ligand shows some additional polar bonds with the other residues which…
Answer for Since the protein is homo-dimer, should I get the same binding affinity values of ligand in two monomers?
No, it is not necessary that if a protein is homo-dimer, then…
Answer for I know the binding sites in both monomers, do I have to preserve the attachment of the ligand to these binding sites, to get binding energy?
Yes, since you are well aware of the binding/catalytic sites of the…
Answer for What is the difference between the blind docking and binding site based docking?
Blind docking is done when we do not have any information about…
Answer for How do you predict protein's binding sites?
We do not have to predict binding sites in the proteins which…
Answer for What's the publication charge
There is no publication charge for Bioinformatics Review. The average duration from…
Answer for What is the impact factor of this journal
Bioinformatics Review is yet to get an official impact factor. Our estimates…
Answer for What is the scope of Bioinformatics in India?
In India, Bioinformatics has high hopes as it is still in nascent…
