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How to perform protein structure modeling using I-Tasser stand-alone tool?

I-Tasser stands for the iterative threading assembly refinement is a well-known tool for ab-initio structure modeling of proteins [1]. It uses secondary-structure enhanced profile-profile threading alignment (PPA) [2] and iterative structure assembly simulations using threading assembly refinement program [3]. I-Tasser is used for ab-initio prediction when the similarity of a protein is quite low (<=30%). Mostly, the I-Tasser server [4] is used for this purpose, which can be easily accessed by registering with a valid institutional mail ID.  In this article, we will learn how to predict a protein structure using I-Tasser standalone version. Continue reading “How to perform protein structure modeling using I-Tasser stand-alone tool?” »

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BiR: Impact report – July 2016 & More

As we improve the quality of articles and as we are nearing our first collective birthday, Bioinformatics Review has expanded its reach, opening new avenues. The progress is summarised as below: We have partnered with London Business Conference Group to be official media partner for Discovery Informatics and Analytics Summit 2016 Our scientific articles are starting… Keep Reading

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