LigPlot+ is a bioinformatics software to visually analyze the protein-ligand interactions in 2D . It requires a Java interface to run and can be executed on Ubuntu, Windows, and macOS. In this tutorial, we will install LigPlot+ on Ubuntu.
At first, update and upgrade your system using the following commands:
$ sudo apt-get update
$ sudo apt-get upgrade
Also, Ligplot+ requires the latest version of the Java SE Runtime Environment (JRE) which can be found here.
The latest version of LigPlot  can be downloaded from here. You have to register yourself first which will be valid for a year. It can be easily downloaded again.
Open a terminal and change to the directory where you have downloaded the software. Let’s say here it is ‘Downloads’.
$ cd Downloads
$ unzip LigPlus.zip
Open a terminal and type the following command:
$ java -cp /path/ -jar LigPlus.jar
here /path/ is the path to the directory where the LigPlus.jar file is located.
It will open the LigPlot+.
You can also create an alias.
Open the terminal and type the following commands:
$ sudo gedit ~/.bashrc
It will open the bashrc file, go to the end of the file and add the following command:
alias ligplus='java -cp /path/LigPlus/ -jar /path/LigPlus.jar'
Save the file, go back to the terminal and type:
$ source ~/.bashrc
To start, Ligplot+, type
$ ligplus in a terminal.
- Laskowski, R. A., & Swindells, M. B. (2011). LigPlot+: multiple ligand-protein interaction diagrams for drug discovery.
- Wallace, A. C., Laskowski, R. A., & Thornton, J. M. (1995). LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. Protein engineering, design and selection, 8(2), 127-134.
[Tutorial] Performing docking using DockingPie plugin in PyMOL.
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DockingPie  is a plugin of PyMOL  made to fulfill the purpose of docking within the PyMOL interface. This plugin will allow you to dock using four different algorithms, namely, Vina, RxDock, SMINA, and ADFR. It will also allow you to perform flexible docking. Though the installation procedure is the same for all OSs, in this article, we are installing this plugin on Ubuntu (Linux).
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[Tutorial] Installing Pyrx on Windows.
How to solve ‘Could NOT find CUDA: Found unsuitable version “10.1”‘ error during GROMACS installation?
Compiling GROMACS  with GPU can be trivial. Previously, we have provided a few articles on the same. In this article, we will solve an error frequently occurring during GROMACS installation.
Installing Autodock4 on MacOS.
How to install Autodock4 on Ubuntu?
DS Visualizer: Uses & Applications
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