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Sequence Analysis - page 2

Role of Information Theory, Chaos Theory, and Linear Algebra and Statistics in the development of alignment-free sequence analysis

in Algorithms/Sequence Analysis/Softwares by

Sequence alignment is a customary to not only find similar regions among a pair of sequences but also to study the structural, functional and evolutionary relationship between organisms. Many tools have been discovered to achieve the goal of alignment of a pair of sequences, separately for nucleotide sequence and amino acid sequence, BLOSSUM & PAM [1] are a few to name. Continue reading “Role of Information Theory, Chaos Theory, and Linear Algebra and Statistics in the development of alignment-free sequence analysis” »

A short introduction to protein structures modification and ModFinder

in Sequence Analysis/Softwares/Tools by

A lot of protein structures are determined on a large scale and submitted in Protein Data Bank (PDB) www.rcsb.org [1]. After the experimental determination of these structures, they are used in many scientific studies and experiments are performed upon them such as mutagenesis, docking, and so on. Continue reading “A short introduction to protein structures modification and ModFinder” »

Alignment-free approaches for Sequence Analysis

in Algorithms/Sequence Analysis/Tools by

Multiple Sequence Alignment (MSA) is a fundamental aspect of Bioinformatics in order to identify the species, their functions, phylogeny, study the novel genes/ proteins, and so on. Multiple MSA tools are available with different specifications, which are based on the heuristic algorithm focusing on the speed rather than the accuracy. Continue reading “Alignment-free approaches for Sequence Analysis” »

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