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[Tutorial] Installing Rosetta 3.21 on Ubuntu

Dr. Muniba Faiza

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Installing Rosetta on Ubuntu

Rosetta is a bioinformatics software for modeling and protein structure analysis [1]. In this article, we are going to install this software on Ubuntu.

Preparing system

Open a terminal by pressing Ctrl+Alt+T. Update and upgrade your system using the following commands:

$ sudo apt-get update

$ sudo apt-get upgrade

Downloading Rosetta

To download Rosetta, you need to obtain a license that is free for academic users. Request a license from here.

After obtaining the license, download the software (tar file) in a directory, let’s say Downloads.

Installing Prerequisites

To install Rosetta on your system, you need to install another software called SCons. Paste the following command.

$ sudo apt-get install -y scons

Installing Rosetta

Change to the directory where you have downloaded the software.

$ cd Downloads/

Extract the downloaded file using the following command.

$ tar xvzf rosetta_src_3.12_bundle.tgz

It will create a new directory, namely, rosetta_src_2020.08.61146_bundle‘. Now, move inside the new directory and install using the following commands.

$ cd rosetta_src_2020.08.61146_bundle/main/source/

$ ./scons.py -j 4 bin

It will take a few minutes to finish installing. After that, you are ready to use Rosetta onUbuntu.


References

  1. https://www.rosettacommons.org/software

Dr. Muniba is a Bioinformatician based in New Delhi, India. She has completed her PhD in Bioinformatics from South China University of Technology, Guangzhou, China. She has cutting edge knowledge of bioinformatics tools, algorithms, and drug designing. When she is not reading she is found enjoying with the family. Know more about Muniba

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