Enzymes are natural biocatalysts and an attractive alternative to chemicals providing improved efficiency for biochemical reactions. They are widely utilized in industrial biotechnology and biocatalysis to...
Multiple Sequence Alignment (MSA) is a fundamental aspect of Bioinformatics in order to identify the species, their functions, phylogeny, study the novel genes/ proteins, and so...
In order to study gene regulation, it is necessary to identify the target sites of miRNA in mRNA. miRNAs have been the main point of research...
As we have discussed the miRNAs, their formation, and functions (miRNA targets and their functions ) and an overview on some of the available miRNA target prediction tools...
Protein-protein interactions (PPIs) have become necessary in order to study many biological processes. In order to study the PPIs, the binding affinity among the proteins is...
miRNAs are the small endogenous non-coding RNAs having a length less than or ~22 nucleotides. miRNAs are expressed from long transcripts formed in animals, viruses, single-celled eukaryotes...
In this rising era of personalized medicine, drug discovery, data refining, chemical compound databases, drug information, identification of symptoms by various levels of biomarkers, bioinformatics have...
Secondary structure formation and conformational changes play a key role in understanding molecular evolution and its functional aspects. Among DNA, RNA, and Protein, secondary structure analyses...
The identification and assignment of functions of unknown macro molecules has been observed to be faster and reliable than the sequence-based methods. This may be due...
Active learning is a kind of machine learning. Basically in active learning, a learning algorithm is used to perform the desired experiments to produce a desired...
When it comes to bioinformatics algorithms, Genetic algorithms top the list of most used and talked about algorithms in bioinformatics. Understanding the Genetic algorithm is important...
T-Coffee is a multiple sequence alignment tool which stands for Tree-based Consistency Objective Function for alignment Evaluation. It is a simultaneous alignment which combines the best...
To study macromolecules in homogenous solution, a technique known as SAXS ( Small Angle X-ray Scattering) is used where the obtained scattering patterns are used to...
CRISPR/Cas9 system is a bacterial defence mechanism against bacteriophage infection. When a viral dna(Bacteriophage, in this case) integrates into the bacterial genome, it produces RNA which...
In my last article I discussed about the Multiple Sequence Alignment and its creation. Now in this article, I am going to explain the workflow of...
Multiple Sequence Alignment (MSA) is a very basic step in the phylogeny analysis of organisms. In MSA, all the sequences under study are aligned together pairwise on...
The new cool word to biological realm “meta-analysis” can be better understood by understanding the meaning of first half of the term; META, meaning data of...
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