Algorithms - Page 2

A collection of articles based on algorithm development in bioinformatics.

BETSY: A new backward-chaining expert system for automated development of pipelines in Bioinformatics

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Bioinformatics analyses have become long and difficult as it involves a large number of steps implemented for data processing. Bioinformatics pipelines are developed to make this process easier, which on one hand automate a specific analysis, while on the other hand, are still limited for investigative analyses requiring changes to the parameters used in the process. Keep Reading

Algorithm and workflow of miRDB

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As mentioned in the previous article, Micro RNAs (miRNAs) are the short endogenous RNAs (~22 nucleotides) and originate from the non-coding RNAs [1], produced in single-celled eukaryotes, viruses, plants, and animals [2]. They play significant roles in various biological processes such as degradation of mRNA [3]. Several databases exist storing a large amount of information about miRNAs, one of such databases miRBase [4] was explained in the previous article, today we will explain the algorithm of miRDB [5,6], another database for miRNA target prediction. Keep Reading

miRBase: Explained

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Micro RNAs (miRNAs) are the short endogenous RNAs (~22 nucleotides) and originate from the non-coding RNAs [1], produced in single-celled eukaryotes, viruses, plants, and animals [2]. miRNAs are capable of controlling homeostasis [2] and play significant roles in various biological processes such as degradation of mRNA and post-translational inhibition through complementary base pairing [3].  Keep Reading

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