MEME suite is used to discover novel motifs in unaligned nucleotide and protein sequences [1,2]. In this article, we will learn how to install MEME on Ubuntu.

Getting started

Let’s update and upgrade the system first.

$ sudo apt-get update

$ sudo apt-get upgrade

Downloading

Change to a directory where you want to download the software. Let’s say Downloads. Open a terminal and type the following commands:

$ cd Downloads/

$ wget http://meme-suite.org/meme-software/5.1.1/meme-5.1.1.tar.gz

Installation

Now extract the package, you will see a new directory called ‘meme-5.1.1‘ in Downloads.  Change to this directory and then install by typing the following commands:

$ tar xvzf meme-5.1.1.tar.gz

$ cd meme-5.1.1/

$ make

$ make test

$ sudo make install

If you don’t see any error, then you have successfully installed the MEME suite on your Ubuntu.

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References

1. Bailey, T. L., Johnson, J., Grant, C. E., & Noble, W. S. (2015). The MEME suite. Nucleic acids research, 43(W1), W39-W49.
2. Bailey, T. L., Boden, M., Buske, F. A., Frith, M., Grant, C. E., Clementi, L., … & Noble, W. S. (2009). MEME SUITE: tools for motif discovery and searching. Nucleic acids research, 37(suppl_2), W202-W208.