Recent advances in in-silico approaches for enzyme engineering
Enzymes are natural biocatalysts and an attractive alternative to chemicals providing improved…
Alignment-free approaches for Sequence Analysis
Multiple Sequence Alignment (MSA) is a fundamental aspect of Bioinformatics in order…
New features to predict miRNA target sites in mRNAs
In order to study gene regulation, it is necessary to identify the…
Common features used to develop miRNA target prediction tools
As we have discussed the miRNAs, their formation, and functions (miRNA targets…
Prediction of Protein-Protein Binding Affinity through their Amino Acid Sequence
Protein-protein interactions (PPIs) have become necessary in order to study many biological…
miRNAs and their Target Prediction Tools: An Overview
miRNAs are the small endogenous non-coding RNAs having a length less than…
DrugQuest: Tool for Drug-associated Queries
In this rising era of personalized medicine, drug discovery, data refining, chemical…
Foldalign: a tool for secondary structure alignment of RNA
Secondary structure formation and conformational changes play a key role in understanding…
WebFEATURE : Tool to identify and visualize Functional Sites in Macromolecules
The identification and assignment of functions of unknown macro molecules has been…
Active learning in drug-target interactions
Active learning is a kind of machine learning. Basically in active learning,…
Genetic Algorithm: Explanation and Perl Code
When it comes to bioinformatics algorithms, Genetic algorithms top the list of…
T-Coffee : A tool that combines both local and global alignments
T-Coffee is a multiple sequence alignment tool which stands for Tree-based Consistency…
Structural Identification of Macromolecules in solution with DARA web server
To study macromolecules in homogenous solution, a technique known as SAXS (…
Explained: CRISPR-ERA and CRISPR/Cas9 system
CRISPR/Cas9 system is a bacterial defence mechanism against bacteriophage infection. When a…
MUSCLE: Tool for Multiple Sequence Alignment
In my last article I discussed about the Multiple Sequence Alignment and…
Basic Concept of Multiple Sequence Alignment
Multiple Sequence Alignment (MSA) is a very basic step in the phylogeny…
Meta-analysis of biological literature : Explained
The new cool word to biological realm “meta-analysis” can be better understood…
