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McPAS-TCR: A database of TCR sequences associated with pathology and antigens

T-cells, also known as T-lymphocytes, play important role in the cell-mediated immune system. T-cells consist of a T-cell receptor (TCR) at their surface which recognizes the foreign and self- origin antigens. These TCRs composed of two chains, namely, TCRα and TCRβ chains which are produced by a random process of DNA rearrangement [1,2]. These TCR repertoires are highly diverse ensuring an effective immune system which cannot be even captured in a blood sample [3]. Continue reading “McPAS-TCR: A database of TCR sequences associated with pathology and antigens” »

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