Previously, we have shown how to analyze Vina output of docking in PyMol [1].
Virtual screening can be difficult for beginners. Here are some FAQs for starters that can help you overcome small issues.
Molecular dynamics (MD) simulation is considered amongst the important methods in bioinformatics. Installation of MD simulation software and execution of their commands is critical. It requires...
EasyVS is a web-based bioinformatics tool that simplifies the selection of the molecular library and its virtual screening [1]. Users can easily perform virtual screening of...
This is a video tutorial of our existing article “Molecular Dynamics (MD) Simulation using GROMACS“.
Some basic operations on multi-FASTA sequence files is a tedious task without using bioinformatics programming. It helps in modifying FASTA sequences or their headers such as...
Differential gene expression analysis helps in discovering quantitative changes in the expression levels between the experimental groups. For that, statistical testing is done using various software....
CRISPR/Cas9 is a genome editing technology trending fastly. It is used to identify CRISPR associated genes within the genomes of prokaryotic bacterias. Several tools are available...
Several errors occur while installing MGLTools and Autodock Vina on Ubuntu. We have explained the complete process of Autodock Vina installation and docking in previous articles....
Here are simple Perl scripts to filter out FASTA sequences from a multi-fasta file based on sequence length.
Gene expression in single cells is measured using single-cell RNA sequencing technology. It helps in finding new and available cell types of different tissues and organs....
It is difficult to manage thousands of compounds altogether while performing virtual high-throughput screening. Compounds databases allow to download of molecules in different formats such as...
Docking software such as Autodock4 [1] and Autodock Vina [2] require input receptor and ligand files in a specific format called pdbqt. Sometimes, preparing files using Autodock...
Previously, we have provided a tutorial on molecular dynamics (MD) simulation of a protein using GROMACS [1] and its result analysis [2]. In this article, we...
SALI MODELLER [1] is one of the most widely used command-line bioinformatics software for protein structure prediction based on homology modeling. The installation of MODELLER on...
Virtual High Throughput Screening (vHTS), also known as Virtual Screening (VS) is one of the essential steps involved in in-silico drug designing. There are several bioinformatics...
Clustal Omega [1,2] and MUSCLE are bioinformatics tools that are used for multiple sequence alignment (MSA). In one of our previous articles, we explained the usage...
In a large file of FASTA sequences, it is nearly impossible to perform some operations manually. This is a simple Perl script to find out duplicate...
Previously, we have explained the initial methods involved in the structure prediction of a protein. In that article, we discussed the three basic methods involved in...
This is a video tutorial of our existing article.
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