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How to perform docking in a specific binding site using AutoDock Vina?

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AutoDock Vina is a bioinformatics tool which is used to perform in- silico docking of proteins with a ligand. It provides many options depending upon the needs of a user. This tool offers blind docking and binding in a specific pocket as well, which is sometimes more demanding when the binding site is already known. This article will guide you to dock a protein with a ligand in a specific binding site/ pocket. Continue reading “How to perform docking in a specific binding site using AutoDock Vina?” »

Methods to detect the effects of alternative splicing and transcription on proteins

in Genomics/Softwares/Tools by

Alternative splicing and the transcription are the most familiar processes amongst the biological processes. Alternative splicing is a process by which various forms of mRNA are generated from the same gene. A gene is consists of various exons and introns and the exons are joined together in different ways [1]. Continue reading “Methods to detect the effects of alternative splicing and transcription on proteins” »

PcircRNA_finder: Tool to predict circular RNA in plants

in Data Mining/Softwares/Tools by

The non-coding circular RNAs (circRNA) play important role in controlling cellular processes. circRNAs are covalently bonded continuous closed loops which originate from the exonic region, known as exonic circRNA, but they can also arise from the intronic and the intergenic regions. Continue reading “PcircRNA_finder: Tool to predict circular RNA in plants” »

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