Connect with us

Tips & Tricks

Bioinformatics- Where & How to Start?

Published

on

How to start with Bioinformatics

Bioinformatics being an interdisciplinary area of biological science and computer science may sound complicated to beginners in this field. However, it is quite simple. The only thing you need is knowledge in both areas. Here is a way for the beginners to start with bioinformatics.

Getting started with Bioinformatics:

1. Learn basic computer languages

Start with learning basic computer languages such as C or C++. Learn to develop algorithm and write simple programs, then you can move on to writing complex programs. Don’t get disappointed while you see multiple errors while executing your code. Solve these errors and you will learn more of it so that you will not make that mistake again.

2. Basic bioinformatics tools

Try hands-on over basic bioinformatics tools such as alignment tools, structure prediction tools, docking, and so on. Read about their algorithms and complete mechanism in their research papers to understand how they work. It will help you in gaining interest in the next programming language you will want to learn. Besides, learn to interpret their output. Using bioinformatics tools is not only about getting results but also about the conclusion. It is important to analyze results to know what information you get after clicking or running commands.

3. Practice more computer languages

Programming is a very important part of bioinformatics. After learning about algorithm development and basic computer languages, practice more languages such as JAVA, PHP, Python, and so on.

4. Work on Linux-based environment

Get command on a Linux-based environment. You can start with Ubuntu. Start with some basic command lines. Read tutorials and install the software in Linux. It will help you to understand how Linux works. Perform some bash commands such as awk, sed, grep, etc., on FASTA files.

5. Write programs

Occasionally, write some programs as they come up in your research. For example, convert file formats using your generated scripts. Try to build some simple tools.

6. Keep yourself updated

Keep yourself updated regarding new tools and techniques in bioinformatics. Read as many research papers as you can. That way you can learn new techniques and biological problems as well. Read about current biological problems and how to solve them.

7. Do simple projects

Start doing some small projects where you can use some tools and write small programs. You can develop tools as well. It will also help you in conducting a research and may add to your skills.

8. Familiarize yourself with web development

Learn to develop and manage databases on servers. Develop a web front for your database and query the database in back-end to display output at the user-front. Google is always at your service. You will find several similar queries on several platforms.

These are the basic steps that can help beginners in getting started with bioinformatics. Try to be proficient in programming. You can always add more.

Tips & Tricks

How to download FASTA sequences from PDB for multiple structures?

Published

on

How to download FASTA sequences from PDB for multiple structures?

In this article, we are going to download FASTA sequences for multiple structures from PDB [1]. We need to have PDB IDs only for input. (more…)

Continue Reading

Software

How to install the LigAlign plugin on Pymol on Ubuntu (Linux)?

Published

on

How to install the LigAlign plugin on Pymol on Ubuntu (Linux)?

Few errors appear when we try to run the LigAlign plugin [1] in Pymol [2]. For example, if you try to run the ligand_alignment plugin, it will give you multiple errors including “Unable to initialize LigAlign v1.00“, or “can’t run LigAlign v1.00” or “incorrect Python syntax” or “Plugin has been installed but initialization failed“. In this article, we explain the reason for this issue and how you can rectify these errors. (more…)

Continue Reading

Tips & Tricks

How to make an impactful science presentation?

Published

on

How to make an impactful science presentation?

After your hard work, it is time to showcase your study and the methods of your study to an audience. You must make every point useful and informative. Here, in this article, we are going to share some tips to make your scientific presentation impactful. (more…)

Continue Reading

LATEST ISSUE

ADVERT